NanobOx named One to Watch at 2022 Massive Concepts showcase | Frost Tech

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Massive concepts this 12 months included an injectable gel therapy for knee osteoarthritis, an AI-powered video abstract, a medical machine to deal with dry eyes, and a software to cut back carbon emissions.

NanobOx has received this 12 months’s Massive Concepts competitors for expertise startups organized by Enterprise Eire. It was one in every of 12 investor-ready startups to current their enterprise fashions at right now’s (November 24) keynote occasion.

NanobOx was launched by Dr. John Favier, a serial entrepreneur who leads the startup as CEO. Favier based NanobOx along with Dr. Mohammad Ghaani at Trinity School Dublin.

The duo have developed extremely energy-efficient expertise to oxygenate water utilizing nanobubbles. Many business bioprocesses require oxygen ranges in course of waters to be maintained at a relentless charge. This is usually a important working price for a course of that may be essential to productiveness.

In aquaculture, or the tradition of fish shares, for instance, the vitality price of oxygenation could be the second highest expense after feeding. It could symbolize 60% to 70% of the working prices in organic wastewater therapy.

Nanobubble era consumes loads of vitality, however with the brand new patented expertise NanobOx has succeeded in lowering the vitality required to take action. Their nanobubble mills could be photo voltaic or battery powered, and with no shifting components, they’re simple to scrub and preserve. The corporate claims its expertise is extremely scalable and may oxygenate water at excessive stream charges.

Fada Medical wins viewers’ selection

Now in its fourteenth 12 months, Massive Concepts held its 2022 launch occasion in entrance of a stay viewers at Croke Park, in addition to a digital viewers on-line.

Massive Concepts showcases deep tech start-up innovation rising from increased schooling institutes. It provides founders direct entry to buyers and the chance to disclose their enterprise thought.

The Massive Concepts pitch groups competed for the One to Watch award, which was determined by a panel of judges. Dwell and on-line audiences additionally chosen the Viewers’ Selection Award winner.

This 12 months, that award went to Fada Medical, which is on a mission to enhance insulin supply for individuals residing with sort 1 diabetes. To do that, Fada Medical has developed novel diffusion expertise that may prolong the time of use of infusion set cannulas, supporting the constant use of insulin pumps over the long run.

Supporting deep expertise

The 12 startups competing within the occasion got three minutes to pitch their improvements and enterprise propositions to an invited in-person and on-line viewers comprised of the Irish analysis and funding communities and the broader startup ecosystem.

Minister of State for Commerce Promotion, Digital and Enterprise Regulation on the Division for Enterprise Commerce and Employment, Dara Calleary, TD, mentioned Eire has one of many “most vibrant and collaborative advertising ecosystems on this planet”.

He additionally emphasised the significance of state funding for progressive corporations. “As these founders face a tougher start-up funding atmosphere, you will need to maintain and assist their development, and devices just like the Disruptive Know-how Innovation Fund play a essential function in addressing potential funding gaps for deep tech startups.

Enterprise Eire CEO Leo Clancy echoed Calleary’s feedback about monetary assist. “Given the extreme world obstacles dealing with Irish companies, it has by no means been extra essential to champion the braveness and ambition of Irish founders, as their spirit and drive are the cornerstones of our native and nationwide economies.

“Enterprise Eire is dedicated to additional accelerating entrepreneurship in Eire and right now’s occasion is a primary instance of this, with the interplay between buyers, increased schooling institutes and our personal assist groups offering these 12 formidable founders the chance to take their companies to the subsequent degree.”

Learn on for particulars on the opposite 10 startups submitting their large concepts.

Darwin and Goliath

This Trinity School Dublin spin-out of the Adapt analysis middle offers carbon calculators that categorize transaction information to find out carbon hotspots and supply suggestions for lowering carbon emissions. The expertise permits corporations to calculate and finally scale back emissions in procurement by evaluating suppliers and displaying emissions info to finish clients.


Giyst, a brand new startup from College School Dublin (UCD), is utilizing AI and machine studying to create video summaries to handle the issues of knowledge overload and brief consideration spans. It’s concentrating on this service at enterprise, schooling and different markets. The aim is to reuse content material to drive higher engagement and discovery.


Infraprint expertise allows stronger 3D printing of engineering plastics than any system in the marketplace. This enables for the fabrication of high-strength, light-weight, customized components in a cost- and time-efficient method. This expertise is especially helpful for small batch element manufacturing, for the aerospace and pharmaceutical industries and past.

Lia Therapeutics

Following needs-based analysis performed in the course of the BioInnovate fellowship program on the College of Galway and a UCD Commercialization Fund, Lia Therapeutics has developed Nightleaf, a drug-free, wearable medical machine to deal with dry eyes and sore.


Dr. Conor Lynch, Researcher and Group Chief on the Nimbus Analysis Middle at Munster College of Know-how, has developed a software to automate vitality saving. His firm, OPEnS, has a grid-connected good grid system that, utilizing vitality market-tracking charge prediction applied sciences, has the power to optimize based mostly on vitality price, carbon emissions, or each concurrently.

pumped coronary heart

Royal School of Surgeons in Eire (RCSI) spin-out Pumpinheart has prototyped a transcatheter implantable diastolic coronary heart pump, PReduction, to deal with late-stage coronary heart failure. The administration workforce has a mix of scientific, engineering and commissioning expertise. Previous to becoming a member of RCSI, CMO Dr. Aamir Hameed was a cardiothoracic surgeon. The CEO, Donald Hickey, is a seasoned entrepreneur in instructional expertise and medical expertise, and the CTO, Dr. Andrew Malone, is a medical physicist.


Having managed tasks for main multinationals equivalent to Roche, Boston Scientific, and Prepare dinner Medical, Dr. Alison Liddy, Co-Founding father of ReleviumBio, has developed an injectable gel therapy to offer superior reduction and safety in opposition to osteoarthritis of the knee. The corporate is concentrating on the knee as the primary scientific indication and plans to increase the therapy indications to give attention to different joints affected by osteoarthritis, the place the identical therapy points exist.

TiLT (Transformation in Studying and Coaching)

TiLT has created an enablement answer to make various organizations extra inclusive, as one would not essentially go hand in hand with the opposite. To do that, TiLT doesn’t give attention to coaching particular person unconscious biases, however on altering the norms round social interplay inside a company.


UniDoodle has created a digital software that addresses the difficulty of scholar disengagement in classroom studying. Denise O’Grady, who introduced UniDoodle at Massive Concepts, is a serial edtech entrepreneur who based Way2Pay in 2013. This start-up was not too long ago bought to Evo Funds, a US-based fee expertise supplier.


Age-related macular degeneration (AMD) is a neurodegenerative illness of the retina that impacts as much as 10% of adults older than 65 years. Vzarii has developed gene therapies that concentrate on late-stage dry AMD. These gene remedy applied sciences are the results of pioneering analysis by the Farrar workforce from Trinity School Dublin’s Faculty of Genetics and Microbiology.

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Further reporting by Elaine Burke

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NanobOx named One to Watch at 2022 Big Ideas showcase

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